EU-FINGERS frequently asked questions

What is dementia?

Dementia is an umbrella term used to describe a set of symptoms that can include memory loss, and other thinking abilities severe enough to interfere with daily life. Though dementia generally involves memory loss, having memory loss alone does not mean you have dementia. There are many different types of dementia and these can affect people differently and cause different symptoms.

What is Alzheimer’s disease?

Alzheimer’s disease is a specific type of dementia in which symptoms usually develop slowly and worsen over time. Alzheimer’s disease is the most common cause of dementia, but not everyone with dementia has Alzheimer’s disease.

In people with Alzheimer’s disease, the brain undergoes changes, including the accumulation of proteins called “ß-amyloid” and “Tau” in the brain. The accumulation of these proteins can start more than a decade before clinical symptoms occur.

During the last few years, new conceptual approaches and criteria to describe Alzheimer’s disease have been developed referring to the spectrum of Alzheimer’s disease in three stages: (1) preclinical Alzheimer’s disease, (2) mild cognitive impairment (MCI) due to Alzheimer’s disease, and (3) dementia due to Alzheimer’s disease. You can read more about the changing definition of Alzheimer’s disease here.

Why are we focusing on dementia prevention?

There is currently no available cure for dementia and Alzheimer’s disease. Today, there is a worldwide effort under way to delay the onset of the disease and prevent it from developing. To that end, EU-FINGERS proposes a novel multimodal prevention framework of precision medicine to address the complex nature of dementia, which focuses on the improvement of vascular and lifestyle-based risk factors. The aim is to deliver targeted and timely interventions to effectively prevent and delay dementia

Who is funding and organising this consortium?

The consortium is being organised in several European countries under the coordination of Karolinska Institutet. Over time, other sources of funding will be sought to maintain and grow the EU-FINGERS platform as a whole.

How can I get involved?

Research groups are welcome to contact us to explore areas of collaboration. EU-FINGERS is working to provide a common framework and align main European cohorts in the dementia and Alzheimer’s disease research field.

EURO-FINGERS is an EU Joint Programme –
Neurodegenerative Disease Research (JPND) project.

The project is supported through the following funding organisations under the aegis of JPND – www.jpnd.eu: Finland, Academy of Finland; Germany, Federal Ministry of Education and Research; Spain, National Institute of Health Carlos III; Luxemburg, National Research Fund; Hungary, National Research, Development and Innovation Office; The Netherlands, Netherlands Organisation for Health Research and Development; Sweden, Swedish Research Council.